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Unless, of course, you're able to seduce that co-star crush in real life.
These stars all found love (or, let's be real, just sex with someone hot in some cases) with onscreen siblings, uncles and even parents.
co-star David Henrie, who played the onscreen brother, Justin Russo, to her bewitching Alex. Probably not, considering she's just as passive aggressive as her problematic on-again off-again boyfriend.co-star and onscreen niece Hayden Panettiere for over a year, but their 12-year age gap proved to be too much for them to handle.
Which is probably eating at him now, seeing as Panettiere is expecting with fiance Wladimir Klitschko, who's 13 years older than she is..
The writers picked up on their chemistry, and in an effort to make it less creepy for everyone involved, threw in a plot twist making them biologically unrelated so they could hook up.